There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Rafaela Ribeiro |
| Institution: | University of Minho - Life and Health Sciences Research Institute (ICVS) |
| Department: | Neurosciences |
| Country: | |
| Proposed Analysis: | The hippocampus is one of the main structures involved in the pathophysiology of Alzheimer’s disease, and while its atrophy is one of the main hallmarks of the disease, there are still much to understand how does this atrophy occurs and which factors influence it. Therefore, our aim is to explore different algorithms evaluating the shape of the hippocampus and understand how it is correlated with other factors that affect Alzheimer’s disease course, such as clinical and cognitive data, medical history and other available biomarkers (including genetic information). We hope to not only understand in higher detail how the hippocampus atrophies in Alzheimer’s disease but also potentially use this knowledge associated with other patient information to potentially develop new useful biomarkers that could potentially have a clinical application. |
| Additional Investigators | |
| Investigator's Name: | Ana Coelho |
| Proposed Analysis: | The hippocampus is one of the main structures involved in the pathophysiology of Alzheimer’s disease, and while its atrophy is one of the main hallmarks of the disease, there are still much to understand how does this atrophy occurs and which factors influence it. Therefore, our aim is to explore different algorithms evaluating the shape of the hippocampus and understand how it is correlated with other factors that affect Alzheimer’s disease course, such as clinical and cognitive data, medical history and other available biomarkers (including genetic information). We hope to not only understand in higher detail how the hippocampus atrophies in Alzheimer’s disease but also potentially use this knowledge associated with other patient information to potentially develop new useful biomarkers that could potentially have a clinical application. |
