There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | QI ZENG |
| Institution: | Icahn School of Medicine at Mount Sinai |
| Department: | genetic and genomics department |
| Country: | |
| Proposed Analysis: | A longitudinal study combine genetic variant, PET, MRI together to detect new biomarker to predict cortical atrophy. Trace back AD patients’ changes from Normal to MCI to AD, ROIs could be identified that are significantly related to AD progression and at the same time differentiable from control at normal stage. Then run anunbiased estimation of genetic variants that predict the ROIs with regression, then compare against genetic variants that be reported to be relevant to beta amyloid and tau disposition. In this way, we could construct a genetic-pathology-morphology chain for better understanding the mechanism undergoing AD progression. |
| Additional Investigators |
