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Principal Investigator  
Principal Investigator's Name: Guanan Zhao
Institution: Lishui city people's hospital
Department: Department of General Surgery
Country:
Proposed Analysis: In this study, we compared levels of transferrin in plasma among individuals with normal cognition (NC), individuals with mild cognitive impairment (MCI), and patients with mild AD dementia from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort. Second, the cross-sectional relationships between plasma transferrin and MMSE scores were examined across three diagnostic groups. Third, linear mixed model was utilized to examine the association of plasma transferrin and changes in MMSE scores over time in the whole sample. Finally, to examine whether this longitudinal association was modified by different disease stages, linear mixed models were performed separately across three diagnostic groups.
Additional Investigators  
Investigator's Name: Jingjing Guan
Proposed Analysis: In this study, we compared levels of transferrin in plasma among individuals with normal cognition (NC), individuals with mild cognitive impairment (MCI), and patients with mild AD dementia from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort. Second, the cross-sectional relationships between plasma transferrin and MMSE scores were examined across three diagnostic groups. Third, linear mixed model was utilized to examine the association of plasma transferrin and changes in MMSE scores over time in the whole sample. Finally, to examine whether this longitudinal association was modified by different disease stages, linear mixed models were performed separately across three diagnostic groups.