There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Joseph Park |
| Institution: | Massachusetts General Hospital/Harvard Medical School |
| Department: | Neurology |
| Country: | |
| Proposed Analysis: | The identification of Alzheimer's disease-related genes/mechanisms which are making impact on specific regions by matching with MRI images. To construct a gene network, correlations or associations among pairs of genes will be obtained by using a random forest-based method to classify significant GGIs from gene expression data. To train the model, we will define novel feature sets and utilised various high-confidence interactome datasets to deduce the correct answer set from known disease-specific genes. Annotated images accompanied with RNA sequencing data will be used to provide informative features for classification, prediction, and pattern discovery. |
| Additional Investigators |
