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Principal Investigator  
Principal Investigator's Name: Maryam Zokaeinikoo
Institution: Pennsylvania State University
Department: Engineering
Country:
Proposed Analysis: Developing interpretable prediction models can build trust especially in the healthcare domain. In recent years, deep learning models have performed promisingly in various applications including computer vision, audio processing, and natural language processing. However, deep learning models are black-box models, which make their application difficult in healthcare due to a lack of interpretability. In this study, we plan to develop an interpretable hierarchical deep neural network for patients' MRI screening to detect the onset of Alzheimer's disease. In addition, we aim to develop an interpretable model that can tell clinicians which part of the brain gets gradually affected by Alzheimer's progression. This MRI dataset can help us dramatically to perform this valuable research. We really appreciate your help. Best Regards
Additional Investigators  
Investigator's Name: Prasenjit Mitra
Proposed Analysis: In this study, we plan to use ADNI dataset to detect the onset of Alzheimer's disease by using deep neural networks. Our model is going to be trained on MRI data to learn the memory loss pattern. We also aim to develop an interpretable model that can inform clinicians why the patient may have Alzheimer's and how the disease is going to progress by the course of time. ADNI dataset play an important roll in this study. We really appreciate your consideration. Thanks