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Principal Investigator  
Principal Investigator's Name: Igor Koval
Institution: Brian and Spine Institute
Department: Inria
Country:
Proposed Analysis: Study of longitudinal trajectories at a population and individual level to better describe the natural history of the disease. This goes together with a better prediction of the future stages at the individual level, especially the characterization of the different features (cortical thickness, cognitive assessments, PET) at 3 and 4 years in advance, along with their relation cofactors (gender, environmental factors, genetic mutation).
Additional Investigators  
Investigator's Name: Etienne Maheux
Proposed Analysis: Study of longitudinal trajectories at a population and individual level to better describe the natural history of the disease. This goes together with a better prediction of the future stages at the individual level, especially the characterization of the different features (cortical thickness, cognitive assessments, PET) at 3 and 4 years in advance, along with their relation cofactors (gender, environmental factors, genetic mutation).