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Principal Investigator  
Principal Investigator's Name: Julie Novakova Martinkova
Institution: Second Faculty of Medicine, Charles University
Department: Department of Neurology
Country:
Proposed Analysis: Examining the relationship between cerebrovascular risk factors, cognition, white matter lesions (white matter hyperintensities volume) and white matter integrity (DTI measures such as regional fractional anisotropy and mean diffusivity) in cognitively unimpaired, MCI due to AD and dementia due to AD. Examining the effect of other variables - especially sex, ApoE status, age, education and diagnosis. The statistical analyses will include multivariable linear regression, mediation analysis and structural equation modeling.
Additional Investigators