There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
Principal Investigator | |
Principal Investigator's Name: | Amin Haghani |
Institution: | University of California Los Angeles |
Department: | Human Genetics |
Country: | |
Proposed Analysis: | The analysis is about the association of brain DNA methylation changes and AD associated neuropathology. We are going to develop an epigenetic model of brain aging, and estimate the rate of age accelaration in brain samples. Next we will examine the association of rate of aging with AD associated pathology. |
Additional Investigators | |
Investigator's Name: | Steve Horvath |
Proposed Analysis: | The project is about deveoping a brain aging DNA methylation model that can predict AD pathology. My lab is experienced in developing epigentic clocks as biomarkers of aging associated diseases. This project will optimize the model in brain samples with higher predictability for AD pathology and progress. |