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Principal Investigator  
Principal Investigator's Name: Sebastian Markett
Institution: Humboldt Universität zu Berlin
Department: Psychology
Country:
Proposed Analysis: We plan to investigate topological aspects of gray matter atrophy and amyloid deposition in patients with AD, MCI and healthy control. We plan to analyze data on the basis the Freesurfer cortical and subcortical parcellation (Design Killiany Atlas). We will use connectome data from a different data source to characterize each brain region via its connectivity pattern. We will then examine whether brain regions' connectivity pattern can predict the degree of atrophy and amyloid in patients. We plan to use MRI data from ADNI (atrophy) and PET from ADNIGO/2.
Additional Investigators  
Investigator's Name: Olga Wudarczyk
Proposed Analysis: We plan to work on the project together (amyloid and atrophy in relationship to white matter connectivity and network topology).