There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Helen Piontkivska |
| Institution: | Kent State University |
| Department: | Biological Sciences |
| Country: | |
| Proposed Analysis: | We are interested in elucidating molecular mechanisms underlying neurodegenerative disorders such as Alzheimer disease (AD), in particular, the role of differential gene regulation and post-transcriptional modifications as facilitators of disease progression and/or changes in associated neuroplasticity. We plan to use the data to examine whether changes in expression networks and/or RNA editing landscapes are linked with specific phenotypes and/or clinical symptoms, and if so, to build a model utilizing specific patterns as early biomarkers of AD or other neurodegenerative conditions. |
| Additional Investigators |
