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Principal Investigator  
Principal Investigator's Name: Cailong Liu
Institution: The First Affiliated Hospital of Wenzhou Medical University
Department: Department of Orthopaedics
Country:
Proposed Analysis: Although emerging evidence suggests a link between osteoarthritis (OA) and risk of dementia, little is known about the association between OA and structural neuroimaging markers. This study aimed to examine the association of OA with change in structural neuroimaging markers among non-demented older people. We examined the cross-sectional and longitudinal relationships between OA and structural neuroimaging markers (hippocampal volume, entorhinal volume, ventricular volume and volume of gray matter of the whole brain) among non-demented older people. We categorized our participants into two OA groups: OA- group and OA+ group.
Additional Investigators  
Investigator's Name: Lichuang Wu
Proposed Analysis: Although emerging evidence suggests a link between osteoarthritis (OA) and risk of dementia, little is known about the association between OA and structural neuroimaging markers. This study aimed to examine the association of OA with change in structural neuroimaging markers among non-demented older people. We examined the cross-sectional and longitudinal relationships between OA and structural neuroimaging markers (hippocampal volume, entorhinal volume, ventricular volume and volume of gray matter of the whole brain) among non-demented older people. We categorized our participants into two OA groups: OA- group and OA+ group.
Investigator's Name: Xiang Wang
Proposed Analysis: Although emerging evidence suggests a link between osteoarthritis (OA) and risk of dementia, little is known about the association between OA and structural neuroimaging markers. This study aimed to examine the association of OA with change in structural neuroimaging markers among non-demented older people. We examined the cross-sectional and longitudinal relationships between OA and structural neuroimaging markers (hippocampal volume, entorhinal volume, ventricular volume and volume of gray matter of the whole brain) among non-demented older people. We categorized our participants into two OA groups: OA- group and OA+ group.