There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Zhenjing Shi |
| Institution: | The Third Affiliated Hospital of Wenzhou Medical University |
| Department: | Department of Intervention |
| Country: | |
| Proposed Analysis: | Accumulating evidence has suggested that neuroinflammation plays a pivotal role in the pathogenesis of Alzheimer’s disease (AD). In this study, we aimed to examine if patterns of CSF inflammatory markers are correlated with global cognition, episodic memory, hippocampal volume, and CSF AD-related pathologies among non-demented older people. Hierarchical cluster analysis including nine inflammatory markers in CSF [Tumor necrosis factor-α(TNF-α), TNF-R1, TNF-R2, transforming growth factor- β1 (TGF-β1), TGF-β2, TGF-β3, Interleukin -21 (IL-21), IL-6, and IL-7] was conducted. |
| Additional Investigators | |
| Investigator's Name: | Yangdi Peng |
| Proposed Analysis: | Accumulating evidence has suggested that neuroinflammation plays a pivotal role in the pathogenesis of Alzheimer’s disease (AD). In this study, we aimed to examine if patterns of CSF inflammatory markers are correlated with global cognition, episodic memory, hippocampal volume, and CSF AD-related pathologies among non-demented older people. Hierarchical cluster analysis including nine inflammatory markers in CSF [Tumor necrosis factor-α(TNF-α), TNF-R1, TNF-R2, transforming growth factor- β1 (TGF-β1), TGF-β2, TGF-β3, Interleukin -21 (IL-21), IL-6, and IL-7] was conducted. |
