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Principal Investigator  
Principal Investigator's Name: Ted Kheng Siang Ng
Institution: National University of Singapore
Department: Psychological Medicine
Country:
Proposed Analysis: First, we aim to examine if biomarkers related to cognitive impairment and Alzheimer’s diseases, namely BDNF, CRP, AB-42, Tau, and p-Tau, have significantly different levels in MCI compared to healthy controls , specifically in the ADNI cohort. Second, we investigate if there are significant associations between BDNF and hs-CRP, AB-42, Tau, and p-Tau. Third, to determine if there are significant associations between the biomarkers with neurocognitive tests and neuroimaging measures, in separate regression models, controlling for other biomarkers.
Additional Investigators