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Principal Investigator  
Principal Investigator's Name: Hongtu Zhu
Institution: University of North Carolina at Chapel Hill
Department: Biostatistics
Country:
Proposed Analysis: We aim to develop novel statistical modeling and machine learning methods in prediction of the Alzheimer's Disease, by using brain structural and functional measures from the T1, resting-state and diffusion weighted MR images. We will further improve the prediction accuracy by integration of both the genetic and imaging biomarkers.
Additional Investigators  
Investigator's Name: Tengfei Li
Proposed Analysis: We will use the ADNI dataset as a validation set to test our imaging-genetic analysis results from UKBiobank data. The ADNI dataset will validate our findings on the identified SNPs associated with brain anatomical/functional measures, Alzheimer's disease status and aging process.
Investigator's Name: Tengfei Li
Proposed Analysis: We will use the ADNI dataset as a validation set to test our imaging-genetic analysis results from UKBiobank data. The ADNI dataset will validate our findings on the identified SNPs associated with brain anatomical/functional measures, Alzheimer's disease status and aging process.