There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Richard Parker |
| Institution: | IXICO Plc |
| Department: | R&D |
| Country: | |
| Proposed Analysis: | Data will be used to help design and validate several automated image processing pipelines, as described below: i) a pipeline to automatically identify the anterior and posterior commissural landmarks. Requested data will be used to form a reference database of manually-labelled subjects, which help to process new images ii) a pipeline for free water estimation from single-shell diffusion MRI data. Requested data will be used to validate the efficacy of free water-based measures (previous studies have shown that free water dMRI endpoints can be used to distinguish diseased patients from healthy controls) iii) a "BrainAGE" pipeline, in which a machine learning algorithm is trained to predict subject age from a large multi-centre cohort of structural scans, after which model residuals (difference in "brain age" vs actual age) forms a useful clinical index. |
| Additional Investigators |
