There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Nazib M Seidu |
| Institution: | Gothenburg University |
| Department: | Psykiatri |
| Country: | |
| Proposed Analysis: | What do we know about CSF neurogranin in relation to volumetric brain regions in preclinical AD? A machine learning (ML) approach. Objective: To use a robust machine leaning model to analyse the relations between the postsynaptic protein neurogranin (Ng) in CSF and large-scale adjusted ICV MRI volumetric brain regions in a clinically CU population-based sample. We further use shrinkages approach (LASSO, Ridge and Elastic Net) to perform volumetric variables selections and modelling in the stratified Aβ42 status (Aβ42+/-) sample and in those with or without APOE ε4 allele. |
| Additional Investigators |
