There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Lauren Schmitz |
| Institution: | University of Wisconsin-Madison |
| Department: | La Follette School of Public Affairs |
| Country: | |
| Proposed Analysis: | The proposed analysis will investigate interactions between polygenic risk for Alzheimer's Disease (AD) and clinical information in ADNI on smoking behavior or alcohol use to assess the degree to which genetic risk for AD is moderated by smoking behavior and alcohol consumption. In addition to polygenic scores for AD that are constructed using traditional methods, we will use tissue-specific scores that re-adjust polygenic score weights from genome-wide association studies for AD using functionally annotated data to improve understanding of biological pathways between smoking/alcohol consumption and AD. |
| Additional Investigators | |
| Investigator's Name: | Qiongshi Lu |
| Proposed Analysis: | Dr. Lu currently has access to the ADNI genetic data and his lab will construct the polygenic scores for AD that we will use in the smoking/alcohol/AD analysis. |
| Investigator's Name: | Jiacheng Miao |
| Proposed Analysis: | Jiacheng Miao is currently a PhD student in Dr. Lu's lab. He will assist with all data analysis. |
