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Principal Investigator  
Principal Investigator's Name: Peng-Fei Zhang
Institution: Qingdao University
Department: Department of Neurology
Country:
Proposed Analysis: Eating disorders (ED) in dementia are included in the Neuropsychiatric Inventory (NPI) scale used for the assessment of severity and frequency of neuropsychiatric symptoms (NPSs) in demented subjects, ind-icating the significance of these disorders for the patients’ function, outcome and management, as well as their effect on caregivers. In Alzheimer’s disease (AD), although the principal disorder is cognitive impairment, ED are also present. Several authors found that the distinct performance of AD and FTD patients in the domain of ED on NPI, helped in the differential diagnosis of dementia. It was also suggested that ED in AD correlate with the duration and severity of the disease.Although ED have been established as an important characteristic of dementia, the underlying neu-robiology has not been examined extensively and remain to be elucidated. We aim to reveal an association between ED and Aβ or Tau PET, which would prove that ED is involved in the pathogenesis of AD.
Additional Investigators