There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Brian Neal |
| Institution: | San Francisco State University |
| Department: | Mathematics |
| Country: | |
| Proposed Analysis: | I am a graduate student in the MA Mathematics program at San Francisco State University; I am currently conducting my master's thesis research under the advisement of faculty member Dr. Tao He. Our research concerns the development of new statistical methodology for testing the association between a gene set and a multivariate phenotype in high-dimensional data. We wish to apply our method to currently-available preliminary data from the Alzheimer's Disease Neuroimaging Initiative as a way of demonstrating and evaluating the utility of our proposed test. We are currently considering conducting a case study similar to the one found in the following paper (also using ADNI data), in which the volumes of five cortical regions were used as a multivariate phenotype (motivated by the relationship between brain atrophy and AD): Deng Y, He T, Fang R, Li S, Cao H and Cui Y (2020). Genome-wide Gene-Based Multi-Trait Analysis. Front. Genet. 11:437. doi:10.3389/fgene.2020.00437 We intend to submit our research to a journal for publication in the future, in compliance with all items contained in the ADNI data use agreement. |
| Additional Investigators | |
| Investigator's Name: | Tao He |
| Proposed Analysis: | Research advisor for Brian Neal |
