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Principal Investigator  
Principal Investigator's Name: Zoe Kourtzi
Institution: University of Cambridge
Department: Psychology
Country:
Proposed Analysis: Given the difficulties in acquiring PET scans combined with the challenge of accurate prediction of Alzheimer's disease subtypes, we are centring our analysis on two pillars; first, using ADNI cohorts to develop an image translation technique via normalising flow to accurately reconstruct PET images using T1w scans. Second, developing graph based semi-supervised learning techniques to accurately predict the disease subtypes while integrating phenotypical, demographics and cognitive variables. We are aiming to combine these two techniques to ultimately deliver a less invasive, quicker and more accurate pre-symptomatic prediction of Alzheimer's disease.
Additional Investigators  
Investigator's Name: Avraam Papadopoulos
Proposed Analysis: Given the difficulties in acquiring PET scans combined with the challenge of accurate prediction of Alzheimer's disease subtypes, we are centring our analysis on two pillars; first, using ADNI cohorts to develop an image translation technique via normalising flow to accurately reconstruct PET images using T1w scans. Second, developing graph based semi-supervised learning techniques to accurately predict the disease subtypes while integrating phenotypical, demographics and cognitive variables. We are aiming to combine these two techniques to ultimately deliver a less invasive, quicker and more accurate presymptomatic prediction of Alzheimer's disease.
Investigator's Name: Nadia Smith
Proposed Analysis: Given the difficulties in acquiring PET scans combined with the challenge of accurate prediction of Alzheimer's disease subtypes, we are centring our analysis on two pillars; first, using ADNI cohorts to develop an image translation technique via normalising flow to accurately reconstruct PET images using T1w scans. Second, developing graph based semi-supervised learning techniques to accurately predict the disease subtypes while integrating phenotypical, demographics and cognitive variables. We are aiming to combine these two techniques to ultimately deliver a less invasive, quicker and more accurate presymptomatic prediction of Alzheimer's disease.
Investigator's Name: Ignacio Partarrieu
Proposed Analysis: Given the difficulties in acquiring PET scans combined with the challenge of accurate prediction of Alzheimer's disease subtypes, we are centring our analysis on two pillars; first, using ADNI cohorts to develop an image translation technique via normalising flow to accurately reconstruct PET images using T1w scans. Second, developing graph based semi-supervised learning techniques to accurately predict the disease subtypes while integrating phenotypical, demographics and cognitive variables. We are aiming to combine these two techniques to ultimately deliver a less invasive, quicker and more accurate presymptomatic prediction of Alzheimer's disease.
Investigator's Name: Spencer Thomas
Proposed Analysis: Given the difficulties in acquiring PET scans combined with the challenge of accurate prediction of Alzheimer's disease subtypes, we are centring our analysis on two pillars; first, using ADNI cohorts to develop an image translation technique via normalising flow to accurately reconstruct PET images using T1w scans. Second, developing graph based semi-supervised learning techniques to accurately predict the disease subtypes while integrating phenotypical, demographics and cognitive variables. We are aiming to combine these two techniques to ultimately deliver a less invasive, quicker and more accurate presymptomatic prediction of Alzheimer's disease.
Investigator's Name: Jenny Venton
Proposed Analysis: Given the difficulties in acquiring PET scans combined with the challenge of accurate prediction of Alzheimer's disease subtypes, we are centring our analysis on two pillars; first, using ADNI cohorts to develop an image translation technique via normalising flow to accurately reconstruct PET images using T1w scans. Second, developing graph based semi-supervised learning techniques to accurately predict the disease subtypes while integrating phenotypical, demographics and cognitive variables. We are aiming to combine these two techniques to ultimately deliver a less invasive, quicker and more accurate presymptomatic prediction of Alzheimer's disease.
Investigator's Name: Matt Hall
Proposed Analysis: Given the difficulties in acquiring PET scans combined with the challenge of accurate prediction of Alzheimer's disease subtypes, we are centring our analysis on two pillars; first, using ADNI cohorts to develop an image translation technique via normalising flow to accurately reconstruct PET images using T1w scans. Second, developing graph based semi-supervised learning techniques to accurately predict the disease subtypes while integrating phenotypical, demographics and cognitive variables. We are aiming to combine these two techniques to ultimately deliver a less invasive, quicker and more accurate presymptomatic prediction of Alzheimer's disease.
Investigator's Name: May Yong
Proposed Analysis: Given the difficulties in acquiring PET scans combined with the challenge of accurate prediction of Alzheimer's disease subtypes, we are centring our analysis on two pillars; first, using ADNI cohorts to develop an image translation technique via normalising flow to accurately reconstruct PET images using T1w scans. Second, developing graph based semi-supervised learning techniques to accurately predict the disease subtypes while integrating phenotypical, demographics and cognitive variables. We are aiming to combine these two techniques to ultimately deliver a less invasive, quicker and more accurate presymptomatic prediction of Alzheimer's disease.
Investigator's Name: Shujun Wang
Proposed Analysis: Machine learning approaches for imputing longitudinal data as part of the main project
Investigator's Name: Yuanxi Li
Proposed Analysis: Given the difficulties in acquiring PET scans combined with the challenge of accurate prediction of Alzheimer's disease subtypes, we are centring our analysis on two pillars; first, using ADNI cohorts to develop an image translation technique via normalising flow to accurately reconstruct PET images using T1w scans. Second, developing graph based semi-supervised learning techniques to accurately predict the disease subtypes while integrating phenotypical, demographics and cognitive variables. We are aiming to combine these two techniques to ultimately deliver a less invasive, quicker and more accurate presymptomatic prediction of Alzheimer's disease.
Investigator's Name: Michael Burkhart
Proposed Analysis: To apply machine learning methods on trajectory modeling of dementia progression.