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Principal Investigator  
Principal Investigator's Name: Edward Martin
Institution: Cardiff University
Department: Computer Science and Informatics
Country:
Proposed Analysis: I intend to use this data for the following project in Collaboration with Dr. Xianfang Sun of Cardiff University as my supervisor. In short, I intend to use the data to produce a machine learning classifier to distinguish between samples in which a mild cognitive impairment (MCI) is present, and the subject either did or did not go on to develop AD. The full project specification is as follows: "One in five people age 65 or older experience “mild cognitive impairment”, a condition marked by a slight decline in memory, language, or thought. Affected individuals may be prone to forgetting appointments or losing the thread of conversations. They also have a higher-than-average risk of developing the more pronounced cognitive decline of Alzheimer’s disease. Yet for the majority of people, symptoms do not progress. In fact, in some instances, the symptoms can be temporary or reversible. This presents a challenge for diagnosing Alzheimer’s disease early, when those affected have the best chance of benefiting from the limited number of interventions and drug treatments. This project aims to develop a new machine learning algorithm to predict the early stages of Alzheimer’s using PET imaging and molecular data from the Alzheimer’s Disease Neuroimaging Initiative (http://adni.loni.usc.edu/) including 2109 imaging studies from 1002 patients."
Additional Investigators