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Principal Investigator  
Principal Investigator's Name: Yalu Wen
Institution: The University of Auckland
Department: Statistics
Country:
Proposed Analysis: The goal of this project is to develop efficient analytical methods to integrate information from multiple sources to predict Alzheimer's Disease (AD). The specific aims are: 1) Use our recently developed kernel-fusion-based method to integrate multi-level data (e.g., genomic, gene expression and demographic variables) from ADNI study, where complex patterns in multi-level data are captured, and noise and redundant information are efficiently removed. 2) Use our recently developed kernel-fusion-based prediction model to predict AD-related phenotypes (e.g., hippocampus and ventricles), where genomic, gene expression, demographic variables are considered. 3) Develop a hierarchical prediction model to predict the progression of AD, where time-dependent information are integrated with the kernel-fusion method.
Additional Investigators