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Principal Investigator  
Principal Investigator's Name: Minos Kritikos
Institution: Stony Brook University
Department: Public Health
Country:
Proposed Analysis: The study of cerebellar atrophy might allow us to more definitively determine whether World Trade Center (WTC) responders with cognitive impairment (CI) are at increased risk for a known neurodegenerative condition or are instead experiencing an undetermined encephalopathy as a result of their exposures on 9/11/2001. We therefore proposed that examining the location of cerebellar gray matter atrophy may help elucidate and even to differentiate between neuropathological processes, as previously described (6). We hypothesized that 1) WTC responders with CI or PTSD would have evidence of cerebellar atrophy, and 2) the pattern of cerebellar atrophy would be distinct from other common neurodegenerative conditions, as compared to a normative database from ADNI.
Additional Investigators