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Principal Investigator  
Principal Investigator's Name: Lizhuang Yang
Institution: Hefei Institutes of Physical Science,Chinese Academy of Sciences
Department: Institute of Health and Medical Technology
Country:
Proposed Analysis: I would like to apply ADNI data to track the dynamic changes in the complex network of the brain at different stages of the disease process. Dynamic brain functional networks have played an important role in the diagnosis and classification of diseases. At the same time, there are more and more studies on the connectivity characteristics of brain functional networks using the method of graph neural networks. Through the design, we can track and observe the dynamic attribute changes of the brain functional network during the progression from MCI to AD, and find better biomarkers, so as to establish an early prediction model of AD. By combining relevant cognitive testing tasks, we can also explore the brain regions closely related to the decline of cognitive function in AD, so as to help us better understand the mechanism of the occurrence and development of AD.
Additional Investigators