There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Maya Kuang |
| Institution: | Johns Hopkins University |
| Department: | Bioinformatics |
| Country: | |
| Proposed Analysis: | We are investigating potential links between single nucleotide variants associated with Irritable Bowel Disease and Alzheimer's disease. Our primary focus is upon variants occurring within the PGLYRP2 locus. PGLYRP2 is a peptidoglycan recognition protein that plays a role in achieving homeostasis in the gut. However, several publications have also implicated a potential role of PGLYRP2 during neurodevelopment. We will be performing bioinformatic analysis to look for any emerging patterns between IBD-associated variants and Alzheimer’s disease. |
| Additional Investigators | |
| Investigator's Name: | Kalyan Botla |
| Proposed Analysis: | We are investigating potential links between single nucleotide variants associated with Irritable Bowel Disease and Alzheimer's disease. Our primary focus is upon variants occurring within the PGLYRP2 locus. PGLYRP2 is a peptidoglycan recognition protein that plays a role in achieving homeostasis in the gut. However, several publications have also implicated a potential role of PGLYRP2 during neurodevelopment. We will be performing bioinformatic analysis to look for any emerging patterns between IBD-associated variants and Alzheimer’s disease. |
| Investigator's Name: | Kate Gerhardt |
| Proposed Analysis: | We are investigating potential links between single nucleotide variants associated with Irritable Bowel Disease and Alzheimer's disease. Our primary focus is upon variants occurring within the PGLYRP2 locus. PGLYRP2 is a peptidoglycan recognition protein that plays a role in achieving homeostasis in the gut. However, several publications have also implicated a potential role of PGLYRP2 during neurodevelopment. We will be performing bioinformatic analysis to look for any emerging patterns between IBD-associated variants and Alzheimer’s disease. |
| Investigator's Name: | Gabrielle Ko |
| Proposed Analysis: | We are investigating potential links between single nucleotide variants associated with Irritable Bowel Disease and Alzheimer's disease. Our primary focus is upon variants occurring within the PGLYRP2 locus. PGLYRP2 is a peptidoglycan recognition protein that plays a role in achieving homeostasis in the gut. However, several publications have also implicated a potential role of PGLYRP2 during neurodevelopment. We will be performing bioinformatic analysis to look for any emerging patterns between IBD-associated variants and Alzheimer’s disease. |
