There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Yeshin Kim |
| Institution: | Kangwon National University Hospital |
| Department: | Neurology |
| Country: | |
| Proposed Analysis: | As a proxy of cognitive reserve, education is known to have a protective effect against the cognitive decline in Alzheimer’s disease. It is explained that a person with higher education would have ability to resist pathologic burdens through other mechanisms such as changes of functional networks of the brain. However, it is not well known whether there is an association between education and the pathologic burden itself. The aim of this study is to evaluate the association between education and ATN biomarkers in Alzheimer’s disease. The values of CSF amyloid β42, CSF phosphoriated Tau (p-Tau), and 18F-fluorodeoxyglucose-positron emission tomography (FDG PET) brain metabolism will be used as ATN biomarkers. We will analyze the association between education and ATN biomarkers in each group, using a multiple linear regression model after controlling age and sex. |
| Additional Investigators |
