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Principal Investigator  
Principal Investigator's Name: Hongyan Xu
Institution: Augusta University
Department: Population Health Sciences
Country:
Proposed Analysis: High-throughput sequence technologies enable us to easily genotype dozens of single nucleotide polymorphisms (SNPs) within any interesting gene. Such genome-wide SNP data are rapidly growing in disease association studies. The association analysis includes single-SNP and haplotype-based disease associations. Haplotype-based association analysis has several advantages over single-SNP association analysis. We propose to develop novel statistical methods for haplotype-based association using the whole-genome sequencing data from the Alzheimer’s Disease Sequencing Project (ADSP) sponsored by the National Institute of Aging. The application has been approved as project 10335 at NIAGADS DSS.
Additional Investigators