There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Anton Porsteinsson |
| Institution: | University of Rochester |
| Department: | Psychiatry |
| Country: | |
| Proposed Analysis: | To investigate the interaction between cognitive reserve and metabolic reserve in predicting cognitive decline and incident MCI and AD using a cusp catastrophe model. |
| Additional Investigators | |
| Investigator's Name: | FengVankee Lin |
| Proposed Analysis: | to investigate the interaction between cognitive reserve and metabolic reserve in predicting cognitive decline and incident MCI and AD using a cusp catastrophe model. |
| Investigator's Name: | Timothy Baran |
| Proposed Analysis: | Quantification of localized 18F-florbetapir (amyloid) uptake within the brain stratified by clinical diagnostic levels of cognitive impairment The goal of this project is to quantify 18F-florbetapir uptake in different regions of the brain, and correlate these data to patients’ clinical diagnosis with regard to levels of cognitive impairment. This will be accomplished by cross-registering 18F-florbetapir PET images with CT images taken of the same patient. CT images will be segmented to separate relevant regions of the brain, and uptake will be quantified in each of these regions in the cross-registered PET images. The patients’ clinical status at the time of PET imaging will be correlated with 18F-florbetapir uptake to look for regional differences in 18F-florbetapir uptake that may be related to clinical diagnosis. This project would require access to 18F-florbetapir PET images, and the corresponding CT images of these patients. |
