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Principal Investigator  
Principal Investigator's Name: zitong zhao
Institution: Changzhou Institute of Technology
Department: School of Computer Information Engineering
Country:
Proposed Analysis: We know that the ADNI dataset was collected in October 2004, and the main goal was to find some accurate and effective methods to detect the presence of Alzheimer's disease at an early stage and to use biomarkers to track the progression of the disease.My current research is related to Alzheimer's disease and requires some sMRI and fMRI image samples for study.Specifically, sparse learning based elastic network algorithm was used to select the features of structural mri images and functional MRI images respectively after pretreatment, and the important voxel features and functional network connection features were retained.Then, the multi-kernel support vector regression machine was used to regression the genotypes of specific loci. Experimental results on public data sets confirmed the validity of the proposed framework, and biomarkers with a high degree of association with diseases were found in the feature selection process of each mode.
Additional Investigators