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Principal Investigator  
Principal Investigator's Name: Yiqiang Zhan
Institution: Karolinska Institutet
Department: Institute of Environmental Medicine
Country:
Proposed Analysis: Polygenic risk score profiling of common risk factors for dementia and their associations with dementia progression in ADNI. In this study, we will apply the state-of-art approaches to construct polygenic risk scores of common risk factors (smoking, BMI, diet, metabolic biomarkers, etc) and to examine their associations with cognitive performance, brain structure/function in patients with AD. We will also use modern machine learning techniques to build prediction models for dementia progression.
Additional Investigators