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Principal Investigator  
Principal Investigator's Name: Keith McGregor
Institution: University of Alabama, Birmingham
Department: Clinical and Diagnostic Sciences
Country:
Proposed Analysis: My laboratory is interested in changes in cortical excitability in aging and in subjective cognitive declines. We use TMS and fMRI/MRS to evaluate changes in excitatory/inhibitory balance. We would like to complete a fMRI connectivity analysis of patients with mild cognitive impairment (MCI) as compared to persons with subjective cognitive decline and older adults without cognitive complaints. We hypothesize that adults with MCI and subjective cognitive decline will have lower intactness of resting state networks than older adults without cognitive complaints.
Additional Investigators  
Investigator's Name: Bryana Whitaker
Proposed Analysis: Bryana Whitaker will be completing an analysis of the motor and default mode networks in this cohort. The proposal is to assess integrity of motor network as predicted by presence and severity of subjective cognitive complaints.
Investigator's Name: Bryana Whitaker
Proposed Analysis: Bryana will be doing an analysis of subjective cognitive decline using resting state data for its relationship to GABA.
Investigator's Name: Aman Vig
Proposed Analysis: Aman will be helping to collate data for the imaging project. He will be organizing the behavioral data.