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Principal Investigator  
Principal Investigator's Name: Zhiqiang Yu
Institution: Nanjing Brain Hospital Affiliated to Nanjing Medical University
Department: Department of neurosurgery
Country:
Proposed Analysis: Alzheimer's disease is the primary cause of dementia worldwide, with an increasing morbidity burden that may outstrip diagnosis and management capacity as the population ages. Current methods integrate patient history, neuropsychological testing and MRI to identify likely cases, yet effective practices remain variably applied and lacking in sensitivity and specificity. Here we aim to identify biomarkers of Alzheimer’s disease (AD) at the earliest possible stage (pre-dementia) by using ADNI’s innovative data. We aim to find out an interpretable deep learning strategy that delineates unique Alzheimer's disease signatures from multimodal inputs of MRI, age, gender, and Mini-Mental State Examination score. For the above reasons, our team hope to apply for permission to ADNI’s innovative data-access.
Additional Investigators