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Principal Investigator  
Principal Investigator's Name: Liming Liang
Institution: Harvard T.H. Chan School of Public Health
Department: Epidemiology
Country:
Proposed Analysis: 1) Perform genome-wide association study for multi-omics data (e.g., expression, metabolites, proteins), MRI imaging data, and derived phenotypes 2) Perform cross-trait genetic analysis between Alzhemer's Disease(AD) and heritable diseases, traits, multi-omics and MRI-derived phenotypes 3) Build polygenic risk score model based on ADNI samples and evaluate external PRS model in ADNI samples for AD-related phenotypes and biomarkers.
Additional Investigators  
Investigator's Name: Zicheng Wang
Proposed Analysis: 1) Perform genome-wide association study for multi-omics data (e.g., expression, metabolites, proteins), MRI imaging data, and derived phenotypes 2) Perform cross-trait genetic analysis between Alzhemer's Disease(AD) and heritable diseases, traits, multi-omics and MRI-derived phenotypes 3) Build polygenic risk score model based on ADNI samples and evaluate external PRS model in ADNI samples for AD-related phenotypes and biomarkers.