There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
Principal Investigator | |
Principal Investigator's Name: | Yi Jie He |
Institution: | The Second Affiliated Hospital of Harbin Medical University |
Department: | Neurology |
Country: | |
Proposed Analysis: | This study proposes to identify datasets of AD serological origin in the ADNI database, screen differentially expressed genes (DEGs) from them for AD versus normal control samples using WGCNA with differential expression analysis, screen Hub genes using multiple machine learning algorithms for diagnostic modelling, and further analyse the role of Hub genes in the immune microenvironment and with the clinical phenotype of AD patients Correlation. To further explore the biomarkers available for early identification of AD. It also provides a theoretical basis for a better understanding of the molecular immune mechanisms of AD. |
Additional Investigators |