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Principal Investigator  
Principal Investigator's Name: zhenliang xiong
Institution: Guizhou University
Department: School of Computer Science and Technology
Country:
Proposed Analysis: We intend to investigate the altered brain function in AD and MCI. First, whole-brain regional homogeneity (ReHo), and the low-frequency fluctuation (ALFF) in each subject will be measured through rs-fMRI approaches. Second, a partial correlation analysis is performed between the altered regions of fMRI image and neuropsychological tests in AD and MCI, and to obtain the behavioral significance of these altered brain functions. Third, the altered ALFF, and ReHo in AD and MCI are integrated to get an imaging biomarker for the prediction of the AD and MCI using the machine learning approach.
Additional Investigators