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Principal Investigator  
Principal Investigator's Name: Sofia Broomé
Institution: Therapanacea
Department: Machine learning R&D
Country:
Proposed Analysis: We are planning to predict clinical status, ADAS-Cog and ventricular volume from the multi-modal input variables found in the ADNI dataset. Our goal is to benchmark several methods for disease progression prediction in Alzheimer’s disease, including statistical, classical machine learning methods as well as deep learning methods. Regarding the deep methods, we will in particular focus on recurrent neural networks and attention-based (Transformer) models in order to model the temporal dimension of the data. We will use the ADNI dataset mainly in the framework of the TADPOLE challenge, i.e. use the D1-D3 splits, but also evaluate splits including newer ADNI data which was not part of TADPOLE to see if this may improve the baselines from the challenge run in 2019.
Additional Investigators  
Investigator's Name: Julia Gachot
Proposed Analysis: We are planning to predict clinical status, ADAS-Cog and ventricular volume from the multi-modal input variables found in the ADNI dataset. Our goal is to benchmark several methods for disease progression prediction in Alzheimer’s disease, including statistical, classical machine learning methods as well as deep learning methods. Regarding the deep methods, we will in particular focus on recurrent neural networks and attention-based (Transformer) models in order to model the temporal dimension of the data. We will use the ADNI dataset mainly in the framework of the TADPOLE challenge, i.e. use the D1-D3 splits, but also evaluate splits including newer ADNI data which was not part of TADPOLE to see if this may improve the baselines from the challenge run in 2019.
Investigator's Name: Audrey Duran
Proposed Analysis: We are planning to predict clinical status, ADAS-Cog and ventricular volume from the multi-modal input variables found in the ADNI dataset. Our goal is to benchmark several methods for disease progression prediction in Alzheimer’s disease, including statistical, classical machine learning methods as well as deep learning methods. Regarding the deep methods, we will in particular focus on recurrent neural networks and attention-based (Transformer) models in order to model the temporal dimension of the data. We will use the ADNI dataset mainly in the framework of the TADPOLE challenge, i.e. use the D1-D3 splits, but also evaluate splits including newer ADNI data which was not part of TADPOLE to see if this may improve the baselines from the challenge run in 2019.
Investigator's Name: Enrica Cavedo
Proposed Analysis: We are planning to predict clinical status, ADAS-Cog and ventricular volume from the multi-modal input variables found in the ADNI dataset. Our goal is to benchmark several methods for disease progression prediction in Alzheimer’s disease, including statistical, classical machine learning methods as well as deep learning methods. Regarding the deep methods, we will in particular focus on recurrent neural networks and attention-based (Transformer) models in order to model the temporal dimension of the data. We will use the ADNI dataset mainly in the framework of the TADPOLE challenge, i.e. use the D1-D3 splits, but also evaluate splits including newer ADNI data which was not part of TADPOLE to see if this may improve the baselines from the challenge.