There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Sangmi Kim |
| Institution: | Syntekabio |
| Department: | - |
| Country: | |
| Proposed Analysis: | We write this mail to inquire possible access to the whole genome data and phenotype information (age, sex etc.) for 800 AD cohorts. We have developed a pipeline specialized in human genome analyses. The pipeline includes standard tools such as NGStoolkit, BWA-MEM and GATK as well as in-house tools to mine SNVs. Its performance appears par to other publically available tools in calling SNVs but impressive in exact genotyping. Using the in-house tools, we have analyzed exome data for > 2500 cohorts, comprised of 661 AFR, 347 AMR, 504 EAS, 503 EUR and 488 SAS collected by 1000 Genome Project. About 90% of 2,500 cohorts was predicted super population by genotype information that out pipeline was analyzed. We specially expect that using the genotype information can be able to predict the super population of race, but also the occurrence of disease. To test our pipeline, we wish to have the whole genome data and phenotype information for the AD cohorts. For your information, Syntekabio is a research oriented company partially owned by Electronics and Telecommunications Research Institute in S. Korea. The company compiled the genome data produced by Korean Genome project, 1000G, and ICGC. We have supercomputing technologies and can easily handle whole genome sequences of several thousand people at a time. Please let us know conditions and regulations to access the data. |
| Additional Investigators |
