There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | hu peng |
| Institution: | The Second Affiliated Hospital of Chongqing Medical University |
| Department: | Department of rehabilitation medicine |
| Country: | |
| Proposed Analysis: | Objective: To investigate the relationship between Alzheimer's disease (AD) and lung function. Hypothesis: The lung has a physiological role in clearing amyloid beta (Aβ), thus it is proposed to obtain brain and lung omics data from the ADNI database, as well as brain and lung PET-CT data from AD patients, to clarify the relationship between AD and lung function and to identify key targets for lung-mediated Aβ clearance. Specific Aim: 1.Retrieve brain and lung omics data from ADNI database. 2.Retrieve brain and lung PET-CT data from AD patients. 3.Analyze the correlation between AD and lung function using statistical methods. 4.Identify potential key targets for lung-mediated Aβ clearance through bioinformatic analysis. 5.Validate the potential targets through in vitro and in vivo experiments. Expected Results: 1.A better understanding of the relationship between AD and lung function. 2.Identification of key targets for lung-mediated Aβ clearance. 3.Potential novel therapeutic targets for AD treatment. |
| Additional Investigators |
