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Principal Investigator  
Principal Investigator's Name: David Inman
Institution: GSK
Department: Biostatistics
Country:
Proposed Analysis: GSK is conducting a Phase II trial in Alzheimer's Disease and are looking to utilize the ADNI data to: Support study design assumptions Evaluate the potential use of concurrent control data to support progression decisions including but not limited to historical data borrowing, prognostic covariate modelling and disease progression models. Analyze cross sectional and longitudinal changes in biomarkers in different subgroups to evaluate natural history and correlate with clinical covariates.
Additional Investigators  
Investigator's Name: David Lunn
Proposed Analysis: As per primary investigator.
Investigator's Name: Doug Thompson
Proposed Analysis: GSK is conducting a Phase II trial in Alzheimer's Disease and are looking to utilize the ADNI data to: Support study design assumptions Evaluate the potential use of concurrent control data to support progression decisions including but not limited to historical data borrowing, prognostic covariate modelling and disease progression models. Analyze cross sectional and longitudinal changes in biomarkers in different subgroups to evaluate natural history and correlate with clinical covariates.
Investigator's Name: Paul Newcombe
Proposed Analysis: GSK is conducting a Phase II trial in Alzheimer's Disease and are looking to utilize the ADNI data to: Support study design assumptions Evaluate the potential use of concurrent control data to support progression decisions including but not limited to historical data borrowing, prognostic covariate modelling and disease progression models. Analyze cross sectional and longitudinal changes in biomarkers in different subgroups to evaluate natural history and correlate with clinical covariates.
Investigator's Name: Tom Taverner
Proposed Analysis: GSK is conducting a Phase II trial in Alzheimer's Disease and are looking to utilize the ADNI data to: Support study design assumptions Evaluate the potential use of concurrent control data to support progression decisions including but not limited to historical data borrowing, prognostic covariate modelling and disease progression models. Analyze cross sectional and longitudinal changes in biomarkers in different subgroups to evaluate natural history and correlate with clinical covariates.
Investigator's Name: Aris Perperoglou
Proposed Analysis: GSK is conducting a Phase II trial in Alzheimer's Disease and are looking to utilize the ADNI data to: Support study design assumptions Evaluate the potential use of concurrent control data to support progression decisions including but not limited to historical data borrowing, prognostic covariate modelling and disease progression models. Analyze cross sectional and longitudinal changes in biomarkers in different subgroups to evaluate natural history and correlate with clinical covariates.
Investigator's Name: Nakul Kamath
Proposed Analysis: GSK is conducting a Phase II trial in Alzheimer's Disease and are looking to utilize the ADNI data to: Support study design assumptions Evaluate the potential use of concurrent control data to support progression decisions including but not limited to historical data borrowing, prognostic covariate modelling and disease progression models. Analyze cross sectional and longitudinal changes in biomarkers in different subgroups to evaluate natural history and correlate with clinical covariates.
Investigator's Name: Harry Parr
Proposed Analysis: GSK is conducting a Phase II trial in Alzheimer's Disease and are looking to utilize the ADNI data to: Support study design assumptions Evaluate the potential use of concurrent control data to support progression decisions including but not limited to historical data borrowing, prognostic covariate modelling and disease progression models. Analyze cross sectional and longitudinal changes in biomarkers in different subgroups to evaluate natural history and correlate with clinical covariates.
Investigator's Name: Dimitra Brintziki
Proposed Analysis: GSK is conducting a Phase II trial in Alzheimer's Disease and are looking to utilize the ADNI data to: Support study design assumptions Evaluate the potential use of concurrent control data to support progression decisions including but not limited to historical data borrowing, prognostic covariate modelling and disease progression models. Analyze cross sectional and longitudinal changes in biomarkers in different subgroups to evaluate natural history and correlate with clinical covariates.
Investigator's Name: Jeffrey Lin
Proposed Analysis: GSK is conducting a Phase II trial in Alzheimer's Disease and are looking to utilize the ADNI data to: Support study design assumptions Evaluate the potential use of concurrent control data to support progression decisions including but not limited to historical data borrowing, prognostic covariate modelling and disease progression models. Analyze cross sectional and longitudinal changes in biomarkers in different subgroups to evaluate natural history and correlate with clinical covariates.