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Principal Investigator  
Principal Investigator's Name: Tracey Colpitts
Institution: Sysmex RDCA Inc.
Department: R&D
Country:
Proposed Analysis: Understand subject characteristics collected by ADNI in preparation for sample application. Sample request will support validation of cutoffs for Sysmex HISCL Amyloid beta 42/40 plasma assay. Positive & Negative predictive values of brain amyloid positivity, as determine by PET, will be assessed.
Additional Investigators  
Investigator's Name: Bingbing Weitner
Proposed Analysis: Understand subject characteristics collected by ADNI in preparation for sample application. Sample request will support the validation of cutoffs for Sysmex HISCL Amyloid beta 42/40 plasma assay. Positive & Negative predictive values of brain amyloid positivity, as determined by PET, will be assessed.
Investigator's Name: Sharbani Phukan
Proposed Analysis: Understand subject characteristics collected by ADNI in preparation for sample application. Sample request will support the validation of cutoffs for Sysmex HISCL Amyloid beta 42/40 plasma assay. Positive & Negative predictive values of brain amyloid positivity, as determined by PET, will be assessed.
Investigator's Name: Miura Masahiro
Proposed Analysis: Understand subject characteristics collected by ADNI in preparation for sample application. Sample request will support the validation of cutoffs for Sysmex HISCL Amyloid beta 42/40 plasma assay. Positive & Negative predictive values of brain amyloid positivity, as determined by PET, will be assessed.
Investigator's Name: Yuji Arimatsu
Proposed Analysis: Understand subject characteristics collected by ADNI in preparation for sample application. Sample request will support the validation of cutoffs for Sysmex HISCL Amyloid beta 42/40 plasma assay. Positive & Negative predictive values of brain amyloid positivity, as determined by PET, will be assessed.
Investigator's Name: Toshikazu Okamura
Proposed Analysis: Understand subject characteristics collected by ADNI in preparation for sample application. Sample request will support the validation of cutoffs for Sysmex HISCL Amyloid beta 42/40 plasma assay. Positive & Negative predictive values of brain amyloid positivity, as determined by PET, will be assessed.
Investigator's Name: Hana Kumamoto
Proposed Analysis: Understand subject characteristics collected by ADNI in preparation for sample application. Sample request will support the validation of cutoffs for Sysmex HISCL Amyloid beta 42/40 plasma assay. Positive & Negative predictive values of brain amyloid positivity, as determined by PET, will be assessed.
Investigator's Name: Yuta Uenoyama
Proposed Analysis: Understand subject characteristics collected by ADNI in preparation for sample application. Sample request will support the validation of cutoffs for Sysmex HISCL Amyloid beta 42/40 plasma assay. Positive & Negative predictive values of brain amyloid positivity, as determined by PET, will be assessed.