There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Jun Lu |
| Institution: | University of Illinois at Chicago |
| Department: | School of Public Health |
| Country: | |
| Proposed Analysis: | This proposed plan aims to explore the use of surrogate endpoints in Phase II clinical trial design to accelerate drug development timelines. We will investigate how surrogate endpoints can provide an early indication of treatment efficacy and help speed up trial progress. To predict the success probability of Phase III trials that utilize surrogate endpoints, we will establish a relationship between the surrogate endpoint and the primary endpoint using novel clinical trial designs and statistical methods. As an example of their application, we will use the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset in this study. |
| Additional Investigators |
