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Principal Investigator  
Principal Investigator's Name: Xin Dong
Institution: the First Affiliated Hospital of Nanjing Medical University
Department: Neurology Department
Country:
Proposed Analysis: We aimed to analyze whether AQP4 genetic variation was related to resting-state brain activity as measured by ALFF, ReHo, and DC in fMRI in a group of AD patients.In addition, we explored the relationship between AQP4-regulated brain changes, cognitive function, and behavioral performance to determine the gene-brain-behavior relationship between AD patients with different gene phenotypes and normal controls.
Additional Investigators  
Investigator's Name: Kezhong Zhang
Proposed Analysis: To determine whether AQP4 genetic variation was related to resting-state brain activity as measured by ALFF, ReHo, and DC in fMRI in a group of AD patients.