There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Isabela Albuja |
| Institution: | University of Pennsylvania |
| Department: | Neurology |
| Country: | |
| Proposed Analysis: | I will be working on this project with Les Shaw and Thomas Tropea. We want to determine whether plasma tau phosphorylated at threonine 181 (p-tau181) distinguishes pathology-confirmed Alzheimer's disease (AD) from normal cognition (NC) adults. We want to derive a cut point that can identify if p-tau181 values above the cut point associate with faster rate of cognitive decline in MMSE. We would like to obtain plasma biomarker and clinical data for AD pathology confirmed cases. |
| Additional Investigators | |
| Investigator's Name: | Leslie Shaw |
| Proposed Analysis: | Determine whether plasma tau phosphorylated at threonine 181 (ptau181) distinguishes pathology-confirmed Alzheimer's disease (AD) from normal cognition (NC) adults. We want to derive a cut point that can identify if ptau181 values p-tau181 values above the cut point associated with faster rate of cognitive decline in MMSE. |
| Investigator's Name: | Thomas Tropea |
| Proposed Analysis: | We want to determine whether plasma tau phosphorylated at threonine 181 (ptau181) distinguishes pathology-confirmed Alzheimer's disease (AD) from normal cognition (NC) adults. We want to derive a cut point that can identify if p-tau181 values above the cut point associated with faster rate of cognitive decline in MMSE. |
