There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Arthur Hamilton |
| Institution: | Carleton University |
| Department: | Department of Cognitive Science |
| Country: | |
| Proposed Analysis: | I will be conducting a cross-sectional analysis on the relationship between white matter hyperintensities (indicating cerebral small vessel disease) and cognitive performance in older adults. I will be using T1-weighted MRI images to standardize the scans from participants to the MNI-152 brain template, and FLAIR MRI images to identify the white matter hyperintensities. I will be investigating whether cognitive reserve factors (from the demographic data) and psychotic symptoms (from the Neuropsychiatric Inventory) mediate the relationship between white matter hyperintensities and cognitive performance. I will be using the ADNI-3 dataset and assessing whether the findings for the above are similar for the different cohorts (cognitively normal, mild cognitive impairment, mild Alzheimer's disease). |
| Additional Investigators | |
| Investigator's Name: | John Anderson |
| Proposed Analysis: | Academic supervisor. Same analysis as described for Arthur Hamilton. |
