There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Zhuqing Zhang |
| Institution: | Affiliated Hospital of Qingdao University |
| Department: | Department of Radiology |
| Country: | |
| Proposed Analysis: | Dear Sir/Madam, I am writing to request access to the Alzheimer's Disease Neuroimaging Initiative (ADNI) database for my research on dynamic brain networks associated with different cognitive performances. My research focuses on investigating the functional connectivity patterns of the brain in individuals with varying cognitive abilities, and I believe that the ADNI dataset would be a valuable resource for my study. I am particularly interested in examining the temporal changes in brain network connectivity in individuals with normal cognitive function, mild cognitive impairment, and Alzheimer's disease. Specifically, I aim to investigate the differences in the dynamic brain network patterns associated with different cognitive performances, and how these patterns evolve over time in relation to the progression of Alzheimer's disease. The ADNI database, which includes neuroimaging, cognitive, and clinical data from thousands of participants across multiple sites, would provide me with a rich source of information to validate my research findings. Furthermore, the longitudinal nature of the ADNI dataset would allow me to examine the temporal dynamics of brain network connectivity in relation to cognitive performance over time. I assure you that I will adhere to the ADNI data-sharing policies and will use the data solely for research purposes. I will also acknowledge the ADNI database in any publications resulting from my research. Thank you for considering my request, and I look forward to the opportunity to use the ADNI database for my research. Sincerely, Zhuqing Zhang |
| Additional Investigators | |
| Investigator's Name: | Han Zhao |
| Proposed Analysis: | Dear Sir/Madam, I am writing to request access to the Alzheimer's Disease Neuroimaging Initiative (ADNI) database for my research on metabolic changes associated with Alzheimer's disease progression. Specifically, I am interested in examining the alterations in metabolites across different stages of the disease, and how these changes are related to the clinical and cognitive characteristics of the participants. My research aims to identify potential biomarkers for Alzheimer's disease using a multi-modal approach that combines neuroimaging and metabolomics data. I believe that the ADNI database, which includes both neuroimaging and metabolomics data from individuals with normal cognitive function, mild cognitive impairment, and Alzheimer's disease, would be a valuable resource for my study. I plan to analyze the metabolomics data from the ADNI database to identify the metabolic pathways that are dysregulated in Alzheimer's disease and how they change over time. I will also investigate the associations between these metabolic changes and clinical and cognitive characteristics, such as amyloid-beta deposition, tau pathology, and cognitive decline. I assure you that I will adhere to the ADNI data-sharing policies and will use the data solely for research purposes. I will also acknowledge the ADNI database in any publications resulting from my research. Thank you for considering my request, and I look forward to the opportunity to use the ADNI database for my research. Sincerely, Han Zhao |
| Investigator's Name: | Zhipeng Guo |
| Proposed Analysis: | Dear Sir/Madam, I am writing to request access to the Alzheimer's Disease Neuroimaging Initiative (ADNI) database for my research on metabolic changes associated with Alzheimer's disease progression. Specifically, I am interested in examining the alterations in metabolites across different stages of the disease, and how these changes are related to the clinical and cognitive characteristics of the participants. My research aims to identify potential biomarkers for Alzheimer's disease using a multi-modal approach that combines neuroimaging and metabolomics data. I believe that the ADNI database, which includes both neuroimaging and metabolomics data from individuals with normal cognitive function, mild cognitive impairment, and Alzheimer's disease, would be a valuable resource for my study. I plan to analyze the metabolomics data from the ADNI database to identify the metabolic pathways that are dysregulated in Alzheimer's disease and how they change over time. I will also investigate the associations between these metabolic changes and clinical and cognitive characteristics, such as amyloid-beta deposition, tau pathology, and cognitive decline. I assure you that I will adhere to the ADNI data-sharing policies and will use the data solely for research purposes. I will also acknowledge the ADNI database in any publications resulting from my research. Thank you for considering my request, and I look forward to the opportunity to use the ADNI database for my research. Sincerely, Zhi-Peng Guo |
