ADNI | Active Investigations

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Active Investigations

There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.

Principal Investigator
Principal Investigator's Name:	Souvik Modi
Institution:	ESYA labs
Department:	Research and Development
Country:
Proposed Analysis:	Our aim is to obtain plasma biomarker data, specifically pTau181, pTau217, NfL, Ab 42/40 ratio, and GFAP concentrations, through Simoa assays. The main goal is to create a multi-analyte combination algorithm that can predict AD in the ADNI cohort. Additionally, we are interested in knowing the ApoE status and amyloid PET (positive or negative) status of these samples. Our secondary objective is to measure the positive and negative predictive value of our multi-analyte assay with PET status.We want to access plasma biomarker data, specifically pTau181, ptau217, NfL, Ab 42/40 ratio and GFAP concentrations measured by Simoa assays. Our primary objective is to develop an multi-analyte combination algorithm for predicting AD in ADNI cohort. Additionally, we wanted to know ApoE status and amyloid PET (positive or negative) status for these samples. Our secondary objective to measure positive and negative predictive value of our multi-analyte assay against the PET status.
Additional Investigators