ADNI | Active Investigations

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Active Investigations

There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.

Principal Investigator
Principal Investigator's Name:	Catherine Clelland
Institution:	Columbia University Irving Medical Center
Department:	Psychiatry
Country:
Proposed Analysis:	We are interested in using genetic polymorphisms as an indicator of gene expression and downstream biomarker level (for example a polymorphism in the GCH1 gene is associated with low GCH1 expression and low tetrahydrobiopterin level). We are looking for association of these biomarker relevant polymorphism with cognition and neuropsychiatric symptoms in AD and MCI.
Additional Investigators
Investigator's Name:	Julia Anderson
Proposed Analysis:	Association between biomarker linked genetic variants with cognition and neurospychiatric symptoms.
Investigator's Name:	James Clelland
Proposed Analysis:	Association between biomarker linked genetic variants with cognition and neurospychiatric symptoms.
Investigator's Name:	Aiden Fel
Proposed Analysis:	Working with the PI, Mr Fel will investigate the association between SNPs in for example, the GCH1 gene, which are know to modulate downstream neurotransmitter levels, with cognition.