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Principal Investigator  
Principal Investigator's Name: Devon Overson
Institution: Duke University
Department: Brain Image and Analysis Center
Country:
Proposed Analysis: Use of single and multi-shell dwi data to determine intra-hippocampal interconnectivity between healthy controls and AD subjects. In addition, determine microstructural neurodegeneration using diffusion-weighted metrics in the cortical structure. I would also like to determine if neurodegeneration can be detected (using the aforementioned methods) for high-risk subjects, such as APOE4 carriers.
Additional Investigators  
Investigator's Name: Trong-Kha Truong
Proposed Analysis: Please see proposed analysis for Devon Overson