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Principal Investigator  
Principal Investigator's Name: Chi Zhang
Institution: ByteDance Ltd.
Department: Strategy and Investment
Country:
Proposed Analysis: Objectives Our team from Bytedance is devoted to finding therapies for patients suffering diseases with high unmet needs. Alzheimer's disease (AD) is a disabilitating disorder with few effective treatment options. ADNI provides a unique opportunity to study AD with a rich longitudinal collection of patient biomarkers, clinical and genetics. We plan to identify potential therapeutic targets from genetics data and understand their mechanism of action (MOA) through associated biomarkers and clinical traits. Analysis plan - We will identify potential therapeutic candidates by performing association analysis with genetics data. - We will evaluate the identified candidates by integrating associated biomarkers, clinical data and gene expression data.
Additional Investigators  
Investigator's Name: Yuli She
Proposed Analysis: Objectives Our team from Bytedance is devoted to finding therapies for patients suffering diseases with high unmet needs. Alzheimer's disease (AD) is a disabilitating disorder with few effective treatment options. ADNI provides a unique opportunity to study AD with a rich longitudinal collection of patient biomarkers, clinical and genetics. We plan to identify potential therapeutic targets from genetics data and understand their mechanism of action (MOA) through associated biomarkers and clinical traits. Analysis plan - We will identify potential therapeutic candidates by performing association analysis with genetics data. - We will evaluate the identified candidates by integrating associated biomarkers, clinical data and gene expression data.