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Principal Investigator  
Principal Investigator's Name: Xiaowei Song
Institution: Dalhousie University
Department: Surrey Memorial Hospital
Country:
Proposed Analysis: We would like to use the ADNI MRI data to validate a brain lesion index (BLI) in construction in the study of AD and aging. We have reported the pilot results at IAGG2009 and received positive feedback. Data from the well-designed ADNI project would help us further develop our research on the BLI, in particular, to improve the generalizability and clinical meaningfulness of the approach. Thank you!
Additional Investigators  
Investigator's Name: David Ward
Proposed Analysis: To construct a lab-based frailty index and to investigate its relationships with the AD diagnosis, biomarkers, risk factors, and outcomes in ADNI 1, GO, 2, and 3. Thank you!
Investigator's Name: Hui Guo
Proposed Analysis: Evaluation of ADNI 1, GO, 2, 3 MRI data for manual construction of the brain atrophy and lesion index and the automation of the whole-brain health assessment, in relation to AD risks and cognition and other health outcomes.